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The Bottom Line on Antioxidant Acitivity
• Lipoic acid is known as a powerful and versatile antioxidant.
• The "lipoic acid" in common supplements is a 50/50 mixture of two different "lipoic acid" molecules: the natural R(+)-lipoic acid, and the unnatural S(-)-form. This mixture is called the "racemate."
• R(+)-lipoic acid is more easily absorbed and taken into the cells than S(-)-lipoic acid.
• Both forms of lipoic acid can be made more powerful by "charging" them up into their DHLA form. R(+)-lipoic acid is upgraded much more rapidly than S(-)-lipoic acid.
• Many studies have found that R(+)-lipoic acid provides much more effective protection than S(-)-lipoic acid or the racemate. In some cases, the S(-)-lipoic acid actually counteracts the effects of R(+)-lipoic acid.
• Common "lipoic acid" supplements are thus like a house at war with itself. The S(-)-form should be removed from supplements in favor of pure R(+)-lipoic acid.
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